Stable composition with high electrolyte content containing an amphiphilic polymer

ABSTRACT

The present invention relates to a composition for topical application, comprising at least one electrolyte and at least one amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion.  
     The invention also relates to the uses of the said composition, especially in cosmetics, to treat and care for human skin, the scalp, mucous membranes, the nails and keratin fibres.

[0001] The present invention relates to a stable composition for topical application, comprising at least one electrolyte and at least one amphiphilic polymer, and to its use especially for treating and caring for human skin, the scalp, mucous membranes, the nails and keratin fibres (hair or eyelashes).

[0002] In the cosmetic, dermatological and pharmaceutical fields, it is known practice to use topical compositions in the form of aqueous gels or of emulsions comprising gelling agents which give these compositions consistency. The majority of the gelling agents conventionally used are carboxyvinyl polymers, which are neutralized with a base.

[0003] However, it is found that certain compounds that it is desired to use in these compositions do not allow the use of the abovementioned gelling agents due to incompatibility.

[0004] It is known, for example, that electrolytes (mineral and organic salts) are incompatible with neutralized carboxyvinyl polymers because they “break” the emulsion and liquefy it. Thus, compositions containing carboxyvinyl polymers and electrolytes lack consistency, which is the opposite of the result desired by the use of a gelling agent.

[0005] Now, it may be desirable to introduce electrolytes into thickened compositions, especially topical compositions, and occasionally even in a relatively large amount, especially when these electrolytes have a beneficial effect on the skin or the hair and are combined with cosmetic and/or dermatological active agents that themselves have beneficial effects on the skin, in particular when the electrolytes are used to reduce the irritation of active agents with an irritant side effect. The gelling agent must be compatible with the electrolytes while at the same time retaining the efficacy of the active agent and of the electrolytes. In addition, the composition must be clear and stable.

[0006] One solution consists in using, instead of carboxyvinyl polymers, gelling agents of polysaccharide type, such as guar gum or xanthan gum or cellulose derivatives. The use of natural gums such as xanthan gum or carrageenans has a tendency to make the products runny and heavy on application. Moreover, compositions based on cellulose derivatives, such as described in document EP-A-654 270, do not have a smooth texture, but instead have a lumpy appearance that looks relatively unpleasant. In addition, these compositions leave the skin sticky and “as if wet” after application, since these compositions do not penetrate sufficiently into the skin. This combination of factors makes them unacceptable for use in cosmetics and/or dermatology.

[0007] Combining these cellulose derivatives with another thickener such as a silicate, as described, for example, in document WO-A-93/8230, gives compositions in which the same drawbacks as mentioned above (lumpy appearance) remain.

[0008] Moreover, crosslinked anionic copolymers comprising 2-acrylamido-2-methylpropanesulphonic groups, such as the product sold by the company SEPPIC under the name Sepigel 305 (consisting of units derived from the reaction between (i) acrylamide, (ii) 2-acrylamido-2-methylpropanesulphonic acid and (iii) at least one compound containing olefinic polyunsaturation) also do not make it possible to obtain compositions containing a large amount of electrolytes while retaining a sufficient viscosity.

[0009] In addition, although the use of 2-acrylamido-2-methylpropanesulphonic acid (AMPS) homopolymers, such as the product sold by the company Clariant under the name Hostacerin AMPS, makes it possible to obtain the gelation of aqueous media while at the same time retaining good cosmetic properties, when compared with other available gelling agents, the addition of electrolytes causes thinning of the gels obtained, that is to say that they lose their viscosity and become more fluid.

[0010] There is thus still a need for gel compositions containing electrolytes, which do not have the drawbacks of the prior art.

[0011] The Applicant has found, unexpectedly, an amphiphilic polymer that makes it possible to stabilize compositions containing electrolytes, without causing the thinning of the said compositions.

[0012] Thus, one subject of the present invention is a composition for topical application, including an aqueous phase comprising at least one electrolyte and at least one amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion.

[0013] Since the composition of the invention is intended for topical application, it comprises a physiologically acceptable medium. In the present patent application, the expression “physiologically acceptable medium” means a medium that is compatible with all keratin materials, such as the skin, including the scalp, the nails, the mucous membranes, the eyes and the hair, or any other area of body skin.

[0014] The composition obtained shows excellent stability and retains a satisfactory viscosity in the presence of electrolyte, even at a high proportion of electrolytes, without unacceptable thinning as is the case for the gelling agents of the prior art.

[0015] Thus, a subject of the present invention is also the use of an amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion, to obtain a stable cosmetic or dermatological composition containing at least one electrolyte.

[0016] The expression “stable composition” means a composition whose viscosity remains virtually constant after addition of electrolyte, or whose viscosity varies within an acceptable limit (for example less than 30% reduction in the viscosity).

[0017] In the present invention, the term “electrolyte” means all salts and polyions, especially polyanions, which may be used in a topical composition.

[0018] The composition obtained is clear and has the desired viscosity, that is to say a viscosity of greater than a few poises, for example from 5 to 80 poises (0.5 to 8 Pa.s), preferably from 10 to 50 poises (1 to 5 Pa.s) and better still from 15 to 30 poises (1.5 to 3 Pa.s), the said viscosity being measured at room temperature (about 25° C.) with a Rheomat 180 using a No. 2, 3, 4 or 5 spindle depending on the viscosity range, at 200 s⁻¹.

[0019] Amphiphilic Polymers According to the Invention

[0020] The polymers in accordance with the invention are amphiphilic polymers comprising at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion.

[0021] The expression “amphiphilic polymer” means any polymer comprising both a hydrophilic portion and a hydrophobic portion and especially a fatty chain.

[0022] The hydrophobic portion present in the polymers of the invention preferably contains from 6 to 50 carbon atoms, more preferably from 6 to 22 carbon atoms, even more preferably from 6 to 18 carbon atoms and more particularly from 12 to 18 carbon atoms.

[0023] Preferably, the polymers in accordance with the invention are partially or totally neutralized with a mineral base (sodium hydroxide, potassium hydroxide or aqueous ammonia) or an organic base such as mono-, di- or triethanolamine, an aminomethylpropanediol, N-methylglucamine, basic amino acids, for instance arginine and lysine, and mixtures of these compounds.

[0024] The amphiphilic polymers in accordance with the invention generally have a number-average molecular weight ranging from 1000 to 20 000 000 g/mol, preferably ranging from 20 000 to 5 000 000 and even more preferably from 100 000 to 1 500 000 g/mol.

[0025] The amphiphilic polymers according to the invention may or may not be crosslinked. Crosslinked amphiphilic polymers are preferably chosen.

[0026] When they are crosslinked, the crosslinking agents may be chosen from compounds containing olefinic polyunsaturation commonly used for the crosslinking of polymers obtained by free-radical polymerization.

[0027] Mention may be made, for example, of divinylbenzene, diallyl ether, dipropylene glycol diallyl ether, polyglycol diallyl ethers, triethylene glycol divinyl ether, hydroquinone diallyl ether, ethylene glycol di(meth)acrylate or tetraethylene glycol di(meth)acrylate, trimethylol propane triacrylate, methylenebisacrylamide, methylenebismethacrylamide, triallylamine, triallyl cyanurate, diallyl maleate, tetraallylethylenediamine, tetraallyloxyethane, trimethylolpropane diallyl ether, allyl (meth)acrylate, allylic ethers of alcohols of the sugar series, or other allyl or vinyl ethers of polyfunctional alcohols, and also allylic esters of phosphoric and/or vinylphosphonic acid derivatives, or mixtures of these compounds.

[0028] Methylenebisacrylamide, allyl methacrylate or trimethylolpropane triacrylate (TMPTA) will be used more particularly. The degree of crosslinking will generally range from 0.01 mol % to 10 mol % and more particularly from 0.2 mol % to 2 mol % relative to the polymer.

[0029] The ethylenically unsaturated monomers containing a sulphonic group are chosen especially from vinylsulphonic acid, styrenesulphonic acid, (meth)acrylamido(C₁-C₂₂)alkylsulphonic acids, N-(C₁-C₂₂)alkyl (meth)acrylamido(C₁-C₂₂)alkylsulphonic acids, for instance undecylacrylamidomethanesulphonic acid, and also partially or totally neutralized forms thereof.

[0030] (Meth)acrylamido(C₁-C₂₂)alkylsulphonic acids such as, for example, acrylamidomethanesulphonic acid, acrylamidoethanesulphonic acid, acrylamidopropane-sulphonic acid, 2-acrylamido-2-methylpropanesulphonic acid, methacrylamido-2-methylpropanesulphonic acid, 2-acrylamido-n-butanesulphonic acid, 2-acrylamido-2,4,4-trimethylpentanesulphonic acid, 2-methacrylamidododecylsulphonic acid or 2-acrylamido-2,6-dimethyl-3-heptanesulphonic acid, and also partially or totally neutralized forms thereof, will more preferably be used.

[0031] 2-Acrylamido-2-methylpropanesulphonic acid (AMPS), and also its partially or totally neutralized forms, will more particularly be used.

[0032] The amphiphilic polymers in accordance with the invention may be chosen especially from random amphiphilic polymers of AMPS modified by reaction with a C₆-C₂₂ n-monoalkylamine or di-n-alkylamine, and such as those described in patent application WO-A-00/31154 (forming an integral part of the content of the description). These polymers may also contain other ethylenically unsaturated hydrophilic monomers chosen, for example, from (meth)acrylic acids, β-substituted alkyl derivatives thereof or esters thereof obtained with monoalcohols or mono- or polyalkylene glycols, (meth)acrylamides, vinylpyrrolidone, maleic anhydride, itaconic acid or maleic acid, or mixtures of these compounds.

[0033] The preferred polymers of the invention are chosen from amphiphilic copolymers of AMPS and of at least one ethylenically unsaturated hydrophobic monomer comprising at least one hydrophobic portion containing from 6 to 50 carbon atoms, more preferably from 6 to 22 carbon atoms, even more preferably from 6 to 18 carbon atoms and more particularly 12 to 18 carbon atoms.

[0034] These same copolymers may also contain one or more ethylenically unsaturated monomers not comprising a fatty chain, such as (meth)acrylic acids, β-substituted alkyl derivatives thereof or esters thereof obtained with monoalcohols or mono- or polyalkylene glycols, (meth)acrylamides, vinylpyrrolidone, maleic anhydride, itaconic acid or maleic acid, or mixtures of these compounds.

[0035] These copolymers are described especially in patent application EP-A-750 899, patent U.S. Pat. No. 5,089,578 and in the following publications from Yotaro Morishima:

[0036] “Self-assembling amphiphilic polyelectrolytes and their nanostructures—Chinese Journal of Polymer Science Vol. 18, No. 40, (2000), 323-336”;

[0037] “Micelle formation of random copolymers of sodium 2-(acrylamido)-2-methylpropanesulfonate and a non-ionic surfactant macromonomer in water as studied by fluorescence and dynamic light scattering—Macromolecules 2000, Vol. 33, No. 10-3694-3704”;

[0038] “Solution properties of micelle networks formed by non-ionic moieties covalently bound to a polyelectrolyte: salt effects on rheological behavior—Langmuir, 2000, Vol. 16, No. 12, 5324-5332”;

[0039] “Stimuli responsive amphiphilic copolymers of sodium 2-(acrylamido)-2-methylpropanesulfonate and associative macromonomers—Polym. Preprint, Div. Polym. Chem. 1999, 40(2), 220-221”.

[0040] The ethylenically unsaturated hydrophobic monomers of these particular copolymers are preferably chosen from the acrylates or acrylamides of formula (I) below:

[0041] in which R₁ and R₃, which may be identical or different, denote a hydrogen atom or a linear or branched C₁-C₆ alkyl radical (preferably methyl); Y denotes O or NH; R₂ denotes a hydrophobic hydrocarbon-based radical containing at least from 6 to 50 carbon atoms, more preferably from 6 to 22 carbon atoms, even more preferably from 6 to 18 carbon atoms and more particularly from 12 to 18 carbon atoms; x denotes a number of moles of alkylene oxide and ranges from 0 to 100.

[0042] The radical R₂ is preferably chosen from linear C₆-C₁₈ alkyl radicals (for example n-hexyl, n-octyl, n-decyl, n-hexadecyl and n-dodecyl) and branched or cyclic C₆-C₁₈ alkyl radicals (for example cyclododecane (C₁₂) or adamantane (C₁₀)); C₆-C₁₈ alkylperfluoro radicals (for example the group of formula —(CH₂)₂—(CF₂)₉—CF₃); the cholesteryl radical (C₂₇) or a cholesterol ester residue, for instance the cholesteryl oxyhexanoate group; aromatic polycyclic groups, for instance naphthalene or pyrene. Among these radicals, the ones that are more particularly preferred are linear alkyl radicals and more particularly the n-dodecyl or n-hexadecyl radical.

[0043] According to one particularly preferred form of the invention, the monomer of formula (I) comprises at least one alkylene oxide unit (x≧1) and preferably a polyoxyalkylenated chain. The polyoxyalkylenated chain preferably consists of ethylene oxide units and/or of propylene oxide units and even more particularly consists of ethylene oxide units. The number of oxyalkylenated units (or number of moles of alkylene oxide) generally ranges from 3 to 100, more preferably from 3 to 50 and even more preferably from 7 to 25.

[0044] Among these polymers, mention may be made of:

[0045] crosslinked or non-crosslinked, neutralized or non-neutralized copolymers comprising from 15% to 60% by weight of AMPS units and from 40% to 85% by weight of (C₈-C₁₆)alkyl(meth)acrylamide units or of (C₈-C₁₆)alkyl (meth)acrylate units relative to the polymer, such as those described in patent application EP-A-750 899;

[0046] terpolymers comprising from 10 mol % to 90 mol % of acrylamide units, from 0.1 mol % to 10 mol % of AMPS units and from 5 mol % to 80 mol % of n-(C₆-C₁₈)alkylacrylamide units, such as those described in U.S. Pat. No. 5,089,578.

[0047] Mention may also be made of copolymers of totally neutralized AMPS and of dodecyl or n-hexadecyl methacrylate, and also crosslinked and non-crosslinked copolymers of AMPS and of n-dodecylmethacrylamide, such as those described in the Morishima articles mentioned above.

[0048] Mention will be made more particularly of the copolymers consisting of 2-acrylamido-2-methylpropanesulphonic acid (AMPS) units of formula (II) below:

[0049] in which X⁺ is a proton, an alkali metal cation, an alkaline-earth metal cation or the ammonium ion, and of units of formula (III) below:

[0050] in which x denotes an integer ranging from 3 to 100, preferably from 5 to 80 and more preferably from 7 to 25; R₁ has the same meaning as that given above in formula (I) and R₄ denotes a linear or branched C₆-C₂₂ and more preferably C₁₀-C₂₂ alkyl.

[0051] The polymers that are particularly preferred are those for which x=25, R₁ denotes methyl and R₄ represents n-dodecyl; they are described in the Morishima articles mentioned above. Other preferred polymers are those for which x=25, R₁ denotes methyl and R₄ represents n-hexadecyl or n-octadecyl.

[0052] The polymers for which X⁺ denotes sodium or ammonium are more particularly preferred.

[0053] The preferred amphiphilic polymers in accordance with the invention may be obtained according to the standard free-radical polymerization processes in the presence of one or more initiators such as, for example, azobisisobutyronitrile (AIBN), azobisdimethylvaleronitrile, 2,2-azobis[2-amidinopropane]hydrochloride (ABAH=2,2-AzoBis[2-Amidinopropane]Hydrochloride), organic peroxides such as dilauryl peroxide, benzoyl peroxide, tert-butyl hydroperoxide, etc., mineral peroxide compounds such as potassium persulphate or ammonium persulphate, or H₂O₂ optionally in the presence of reducing agents.

[0054] The amphiphilic polymers are obtained especially by free-radical polymerization in tert-butanol medium in which they precipitate. Using precipitation polymerization in tert-butanol, it is possible to obtain a size distribution of the polymer particles that is particularly favourable for its uses.

[0055] The size distribution of the polymer particles may be determined, for example, by laser diffraction or image analysis. An advantageous distribution for this type of polymer, determined by image analysis, is as follows: 60.2% less than 423 microns, 52.0% less than 212 microns, 26.6% less than 106 microns, 2.6% less than 45 microns and 26.6% greater than 850 microns.

[0056] The reaction may be performed at a temperature of between 0 and 150° C., preferably between 10 and 100° C., either at atmospheric pressure or under reduced pressure. It may also be performed under inert atmosphere, and preferably under nitrogen.

[0057] According to this process 2-acrylamido-2-methylpropanesulphonic acid (AMPS) or a sodium or ammonium salt thereof was especially polymerized with a (meth)acrylic acid ester and

[0058] a C₁₀-C₁₈ alcohol oxyethylenated with 8 mol of ethylene oxide (Genapol® C-080 from the company Hoechst/Clariant),

[0059] a C₁₁ oxo alcohol oxyethylenated with 8 mol of ethylene oxide (Genapol® UD-080 from the company Hoechst/Clariant),

[0060] a C₁₁ oxo alcohol oxyethylenated with 7 mol of ethylene oxide (Genapol® UD-070 from the company Hoechst/Clariant),

[0061] a C₁₂-C₁₄ alcohol oxyethylenated with 7 mol of ethylene oxide (Genapol® LA-070 from the company Hoechst/Clariant),

[0062] a C₁₂-C₁₄ alcohol oxyethylenated with 9 mol of ethylene oxide (Genapol® LA-090 from the company Hoechst/Clariant),

[0063] a C₁₂-C₁₄ alcohol oxyethylenated with 11 mol of ethylene oxide (Genapol® LA-110 from the company Hoechst/Clariant),

[0064] a C₁₆-C₁₈ alcohol oxyethylenated with 8 mol of ethylene oxide (Genapol® T-080 from the company Hoechst/Clariant),

[0065] a C₁₆-C₁₈ alcohol oxyethylenated with 15 mol of ethylene oxide (Genapol® T-150 from the company Hoechst/Clariant),

[0066] a C₁₆-C₁₈ alcohol oxyethylenated with 11 mol of ethylene oxide (Genapol® T-110 from the company Hoechst/Clariant),

[0067] a C₁₆-C₁₈ alcohol oxyethylenated with 20 mol of ethylene oxide (Genapol® T-200 from the company Hoechst/Clariant),

[0068] a C₁₆-C₁₈ alcohol oxyethylenated with 25 mol of ethylene oxide (Genapol® T-250 from the company Hoechst/Clariant),

[0069] a C₁₈-C₂₂ alcohol oxyethylenated with 25 mol of ethylene oxide and/or a C₁₆-C₁₈ iso alcohol oxyethylenated with 25 mol of ethylene oxide.

[0070] The molar % concentration of the units of formula (II) and of the units of formula (III) in the polymers according to the invention will vary as a function of the desired cosmetic use and of the desired rheological properties of the formulation. It may range between 0.1 mol % and 99.9 mol %.

[0071] Preferably, for the most hydrophobic polymers, the molar proportion of units of formula (I) or (III) ranges from 50.1% to 99.9%, more particularly from 70% to 95% and even more particularly from 80% to 90%.

[0072] Preferably, for the sparingly hydrophobic polymers, the molar proportion of units of formula (I) or (III) ranges from 0.1% to 50%, more particularly from 5% to 25% and even more particularly from 10% to 20%.

[0073] The monomer distribution in the polymers of the invention may be, for example, alternating, block (including multiblock) or random.

[0074] According to the invention, it is preferable for the polymers to contain heat-sensitive pendant chains and for the aqueous solution thereof to have a viscosity that, beyond a certain threshold temperature, increases or remains virtually constant as the temperature increases.

[0075] Even more particularly, the preferred polymers are those whose aqueous solution has a viscosity that is low below a first threshold temperature and that, above this first threshold temperature, increases to a maximum as the temperature increases, and that, above a second threshold temperature, decreases again as the temperature increases. From this perspective, it is preferable for the viscosity of the polymer solutions below the first threshold temperature to be from 5% to 50%, in particular from 10% to 30% of the maximum viscosity at the second threshold temperature.

[0076] These polymers preferably lead in water to a phenomenon of demixing by heating, reflected by curves showing, as a function of the temperature and the concentration, a minimum known as the LCST (Lower Critical Solution Temperature).

[0077] The viscosities (measured at 25° C. using a Brookfield viscometer, needle No. 7) of the aqueous 1% solutions preferably range from 20 000 mPa.s to 100 000 mpa.s and more particularly from 60 000 mpa.s to 70 000 mPa.s.

[0078] The amphiphilic polymers in accordance with the invention are present in the compositions in concentrations ranging from 0.01% to 30% by weight of active material, more preferably from 0.1% to 10% of active material, even more preferably from 0.1% to 5% by weight of active material and even more particularly from 0.2% to 2% by weight of active material relative to the total weight of the composition.

[0079] The electrolyte may be present in the composition of the invention in an amount ranging, for example, from 0.01% to 20% by weight of active material, preferably from 0.01% to 10% and better still from 0.05% to 5% by weight relative to the total weight of the composition. This amount of electrolyte varies especially according to the electrolyte used and the desired aim of the final composition.

[0080] As electrolytes that may be used in the composition according to the invention, mention may be made especially of mono-, di- or trivalent metal salts, and more particularly alkaline-earth metal salts and in particular barium, calcium and strontium salts, alkali metal salts, and for example sodium and potassium salts, and also magnesium, beryllium, yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, lithium, tin, zinc, manganese, cobalt, nickel, iron, copper, rubidium, aluminium, silicon and selenium salts, and mixtures thereof.

[0081] The ions constituting these salts may be chosen, for example, from carbonates, bicarbonates, sulphates, phosphates, sulphonates, glycerophosphates, borates, bromides, chlorides, nitrates, acetates, hydroxides and persulphates, and also ions of α-hydroxy acids (citrates, tartrates, lactates or malates) or of fruit acids, ions of β-hydroxy acids (salicylates, 2-hydroxyalkanoates, n-alkylsalicylates and n-alkanoyl-salicylates), or ions of amino acids (aspartate, arginate, glycocholate or fumarate).

[0082] It is also possible to use a mixture of these salts, including natural mixtures or mixtures whose composition is close to that of a natural mixture, and in particular an aqueous mixture comprising from 30% to 35% magnesium chloride, from 20% to 28% potassium chloride, from 3% to 10% sodium chloride, from 0.2% to 1% calcium chloride, from 0.1% to 0.6% magnesium bromide and from 0.1% to 0.5% insolubles, the said mixture being referred to herein as “Dead Sea bath salts mixture” since it corresponds to the main salts contained in the Dead Sea.

[0083] It is also possible to use salts that are in the form of a solution or a water containing them, and especially in the form of a thermal spring water or mineral water. In general, a mineral water is fit for consumption, which is not always the case for a thermal spring water. Each of these waters contains, inter alia, dissolved minerals and trace elements.

[0084] The thermal spring water or mineral water used may be chosen, for example, from eau de Vittel, waters from the Vichy basin, eau d'Uriage, eau de la Roche Posay, eau de la Bourboule, eau d'Enghien-les-bains, eau de Saint-Gervais-les bains, eau de Néris-les-bains, eau d'Allevard-les-bains, eau de Digne, eau des Maizières, eau de Neyrac-les-bains, eau de Lons le Saunier, Eaux Bonnes, eau de Rochefort, eau de Saint Christau, eau des Fumades, eau d'Avène and eau de Tercis-les-bains.

[0085] The electrolytes of the composition of the invention may also be chosen from the salts of active agents, for example salts derived from vitamins, for instance vitamin C (ascorbic acid) or vitamin A (retinol), or the salts of acidic active agents, for instance the salts of acidic screening agents). Examples of salts derived from vitamins that may be mentioned include the ascorbyl phosphate of an alkali metal, alkaline-earth metal or transition metal, for instance magnesium, sodium, potassium, calcium or zinc; the retinyl phosphate of an alkali metal or alkaline-earth metal, for instance magnesium or potassium. Examples of salts derived from screening agents that may be mentioned include benzene-1,4-[di(3-methylidene-10-camphorsulphonic) acid] salts, the sodium sulphonate of 2-hydroxy-4-methoxy-5-benzophenone acid (or benzophenone-5) and the disodium salt of 2,2′-dihydroxy-4,4′-dimethoxy-5,5′-disulphobenzophenone (or benzophenone-9).

[0086] The physiologically acceptable medium for the composition of the invention comprises water. The amount of water may range from 5% to 99.98% by weight and preferably from 30% to 95% by weight relative to the total weight of the composition. This medium may contain, besides water, one or more solvents chosen from lower alcohols containing from 1 to 8 carbon atoms, such as ethanol; polyols such as glycerol; glycols, for instance butylene glycol, isoprene glycol, propylene glycol, or polyethylene glycols such as PEG-8; sorbitol; sugars such as glucose, fructose, maltose, lactose or sucrose; and mixtures thereof. The amount of solvent(s) in the composition of the invention may range from 0.2% to 30% by weight and preferably from 1% to 20% by weight relative to the total weight of the composition.

[0087] The composition of the invention preferably has a pH that is compatible with the skin, that is to say preferably ranging from 3 to 8 and better still from 5 to 7.

[0088] The composition of the invention may also contain one or more additives that are common in cosmetics and/or dermatology, such as surfactants, active agents, fillers, pigments, nacres, preserving agents, gelling agents, plasticizers, antioxidants, fragrances, odour absorbers, antifoams, sequestering agents (EDTA), acidic or basic pH regulators or buffers, fatty substances, for instance oils or waxes, and mixtures thereof, provided that the additive does not adversely affect the desired properties for the composition of the invention. The amounts of these various additives are those conventionally used in the fields under consideration, and for example from 0.01% to 20% relative to the total weight of the composition.

[0089] The composition according to the invention may be in any pharmacological form that is suitable for topical application, and especially in the form of an aqueous or aqueous-alcoholic gel, an emulsion, especially an O/W emulsion, or an aqueous dispersion based on ionic and/or nonionic lipid vesicles, optionally containing a dispersed oil. It may, for example, constitute a serum, a cream or a milk.

[0090] The composition according to the invention may also contain at least one oily phase.

[0091] When the composition of the invention is an emulsion, the proportion of the fatty phase (or oily phase) may range from 5% to 80% by weight and preferably from 10% to 50% by weight relative to the total weight of the composition, and the proportion of aqueous phase may range from 20% to 95% and preferably from 50% to 90% by weight relative to the total weight of the composition. The oils, emulsifiers and co-emulsifiers used in the composition in emulsion form are chosen from those conventionally used in the field under consideration. The oily phase contains one or more oils, that is to say organic substances that are liquid at room temperature (20 to 25° C.) and at atmospheric pressure (760 mm Hg).

[0092] As oils which can be used in the composition of the invention, mention may be made for example of:

[0093] hydrocarbon-based oils of animal origin, such as perhydrosqualene;

[0094] hydrocarbon-based plant-origin oils such as liquid triglycerides of fatty acids containing from 4 to 10 carbon atoms, such as heptanoic or octanoic acid triglycerides or alternatively, for example, sunflower oil, corn oil, soya bean oil, marrow oil, grapeseed oil, sesame oil, hazelnut oil, apricot oil, macadamia oil, arara oil, castor oil, avocado oil, caprylic/capric acid triglycerides such as those sold by the company Stearineries Dubois or those sold under the names Miglyol 810, 812 and 818 by the company Dynamit Nobel, jojoba oil or karite butter;

[0095] synthetic esters and ethers in particular of fatty acids, such as the oils of formulae R¹COOR² and R¹OR² in which R¹ represents a fatty acid residue containing from 8 to 29 carbon atoms and R² represents a branched or unbranched hydrocarbon-based chain containing from 3 to 30 carbon atoms, such as, for example, purcellin oil, isononyl isononanoate, isopropyl myristate, 2-ethylhexyl palmitate, 2-octyldodecyl stearate, 2-octyldodecyl erucate or isostearyl isostearate; hydroxylated esters such as isostearyl lactate, octyl hydroxystearate, octyldodecyl hydroxystearate, diisostearyl malate, triisocetyl citrate, and fatty alcohol heptanoates, octanoates and decanoates; polyol esters such as propylene glycol dioctanoate, neopentyl glycol diheptanoate and diethylene glycol diisononanoate; and pentaerythritol esters such as pentaerythrityl tetraisostearate;

[0096] linear or branched hydrocarbons of mineral or synthetic origin, such as volatile or non-volatile liquid paraffins and derivatives thereof, petroleum jelly, polydecenes or hydrogenated polyisobutene such as parleam;

[0097] fatty alcohols containing from 8 to 26 carbon atoms, such as cetyl alcohol, stearyl alcohol, and the mixture thereof (cetylstearyl alcohol), octyldodecanol, 2-butyloctanol, 2-hexyldecanol, 2-undecylpentadecanol oleyl alcohol, or linoleyl alcohol;

[0098] partially hydrocarbon-based and/or silicone-based fluoro oils such as those described in document JP-A-2 295 912;

[0099] silicone oils such as volatile or non-volatile polymethylsiloxanes (PDMSs) containing a linear or cyclic silicone-based chain, which are liquid or pasty at room temperature, in particular cyclopolydimethylsiloxanes (cyclomethicones) such as cyclohexasiloxane; polydimethylsiloxanes comprising alkyl, alkoxy or phenyl groups, pendant or at the end of a silicone-based chain, these groups containing from 2 to 24 carbon atoms; phenylsilicones such as phenyl trimethicones, phenyl dimethicones, phenyltrimethyl-siloxydiphenylsiloxanes, diphenyl dimethicones, diphenylmethyldiphenyltrisiloxanes, 2-phenylethyl trimethylsiloxysilicates and polymethylphenylsiloxanes;

[0100] mixtures thereof.

[0101] “Hydrocarbon-based oil” is understood to mean, in the list of oils mentioned above, any oil containing a majority of carbon and hydrogen atoms and optionally ester, ether, fluoro, carboxylic acid and/or alcohol groups.

[0102] The other fatty substances which may be present in the oily phase are, for example, fatty acids containing from 8 to 30 carbon atoms, for instance stearic acid, lauric acid or palmitic acid; waxes, for instance lanolin, beeswax, carnauba wax, candelilla wax, paraffin wax, lignite wax or microcrystalline waxes, ceresine or ozokerite, synthetic waxes, for instance polyethylene waxes and Fischer-Tropsch waxes; gums such as silicone gums (dimethiconol); silicone resins such as trifluoromethyl-C1-4-alkyldimethicone and trifluoropropyldimethicone; and silicone elastomers, for instance the products sold under the names “KSG” by the company Shin-Etsu, under the names “Trefil”, “BY29” or “EPSX” by the company Dow Corning or under the names “Gransil” by the company Grant Industries.

[0103] These fatty substances may be chosen in a varied manner by a person skilled in the art in order to prepare a composition having the desired properties, for example of consistency or of texture.

[0104] According to one particular embodiment of the invention, when the composition is an O/W emulsion, it may be prepared without addition of emulsifiers, by virtue of the amphiphilic nature of the polymer. Thus, due to the absence of an emulsifying surfactant, this emulsion has the advantage of not being irritant to skin that is particularly sensitive and/or reactive, and it can constitute a hypoallergenic product. The polymer used according to the invention thus makes it possible to prepare emulsifier-free oil-in-water emulsions.

[0105] A subject of the invention is thus also an emulsion comprising an oily phase dispersed in an aqueous phase, characterized in that it is free of emulsifier and in that it contains at least one amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion.

[0106] The composition according to the invention may be used in many cosmetic or dermatological applications in which the presence of salts is useful; it may especially be used for treating, caring for and/or making up facial and/or body skin, mucous membranes (lips), the scalp and/or keratin fibres (hair or eyelashes), and also for treating sensitive skin and/or a sensitive scalp. For example, it may be used for moisturizing the skin and for giving the skin a radiant complexion such as an anti-ageing skincare product.

[0107] Thus, the compositions of the invention may be used as care products and/or hygiene products such as protective, treatment or care creams for the face, for the hands or for the body, protective or care body milks, lotions, milks, gels or mousses to care for the skin and mucous membranes or for cleansing, removing make-up from or scrubbing skin. They may also constitute make-up products for keratin fibres, the skin, the lips and/or the nails, such as a foundation, a face powder, an eyeshadow, a lipstick, a mascara or an eyeliner.

[0108] The compositions of the invention may also be used as antisun products for protecting the skin against UV rays.

[0109] Thus, one subject of the present invention is the cosmetic use of the cosmetic composition as defined above, to treat, care for and/or make up the facial and/or body skin, mucous membranes (lips), the scalp and/or keratin fibres.

[0110] A subject of the present invention is also the use of the composition as defined above for the manufacture of a composition intended for treating sensitive skin and/or a sensitive scalp. For further details regarding sensitive skin, reference may be made to document EP-A-680 749.

[0111] Another subject of the invention is a cosmetic process for treating human keratin materials such as the skin, including the scalp, the hair, the eyelashes, the eyebrows, the nails or the mucous membranes, especially the lips, characterized in that a cosmetic composition as defined above is applied to the keratin materials according to the usual technique for using this composition. For example: application of creams, gels, sera, lotions or milks to the skin, the scalp and/or the mucous membranes. The type of treatment depends on the electrolyte(s) present in the composition.

PREPARATION EXAMPLES

[0112] Preparation of Ethoxylated (Meth)Acrylic Esters:

[0113] These may especially be obtained by the action of glycidyl (meth)acrylate or (meth)acrylic acid or an alkyl (meth)acrylate-or a (meth)acryloyl halide on an ethoxylated fatty alcohol. Non-limiting examples which may be mentioned include the following preparations:

[0114] a) starting with glycidyl methacrylate and Genapol T-250;

[0115] b) starting with (meth)acrylic acid and Genapol UD-070;

[0116] c) starting with methyl (meth)acrylate and Genapol LA-090;

[0117] d) starting with (meth)acryloyl chloride and Genapol UD-070.

[0118] a) 500 g of Genapol T-250 and 75 g of glycidyl methacrylate are placed in a one-liter three-necked reactor equipped with a stirrer, a thermometer and a reflux condenser. The reaction mixture is heated at a temperature of 100° C. for 2 hours and the excess glycidyl methacrylate is removed by distillation under reduced pressure. The monomer obtained may be used for the polymerization without further purification.

[0119] b) 500 g of Genapol UD-070, 100 g of (meth)acrylic acid and p-toluenesulphonic acid as catalyst are placed in a one-liter three-necked reactor equipped with a stirrer, a thermometer and a reflux condenser. The reaction mixture is refluxed for 2 hours and the excess acid and the water formed during the reaction are separated out by distillation under reduced pressure. The monomer obtained may be used for the polymerization without further purification.

[0120] c) 500 g of Genapol LA-090, 100 g of methyl (meth)acrylate and 20 g of titanium tetraisopropoxide are placed in a one-liter three-necked reactor equipped with a stirrer, a thermometer and a reflux condenser. The reaction mixture is refluxed for 2 hours and, after separation by distilling off the alcohol formed, the remaining ester is distilled under reduced pressure. The monomer obtained may be used for the polymerization without further purification.

[0121] d) 500 g of Genapol UD-070, 110 g of (meth)acryloyl chloride and 50 g of sodium carbonate are placed in a one-liter three-necked reactor equipped with a stirrer, a thermometer and a reflux condenser. The reaction mixture is refluxed for 2 hours and the excess acid chloride is separated out by distillation under reduced pressure. The monomer obtained may be used for the polymerization without further purification.

[0122] Polymerization According to the Precipitation Method in Tert-Butanol

[0123] 500 ml of tert-butanol and the calculated amount of AMPS are placed in a 2-liter reactor equipped with a reflux condenser, a gas inlet, a thermometer and a stirrer. The mixture is neutralized by introducing NH₃, and the monomer prepared above is added to the reaction mixture. The reaction mixture is made inert by passing nitrogen or argon through, and, when the internal temperature has reached 60° C., the initiator (AIBN) is introduced to initiate the polymerization. After a few minutes, the polymer thus prepared precipitates. The mixture is maintained at reflux for 2 hours, and the polymer is separated from the solvent by vacuum filtration and then dried under reduced pressure.

[0124] The following polymers were prepared in the manner described above:

[0125] (starting with the following reagents in amounts expressed in grams) Genapol T-250 methacrylate 10 20 30 97 AMPS neutralized with NH₃ 90 80 90 3 Methylenebisacrylamide 1.5 (crosslinking agent) Allyl methacrylate 1.7 (crosslinking agent) TMPTA (crosslinking agent) 1.8 1.8 Azobisisobutyronitrile 1 (initiator) Dilauryl peroxide (initiator) 1 1 1 tert-Butanol 300 300 300 300

[0126] The following were prepared in the same manner:

[0127] a copolymer crosslinked with allyl methacrylate, consisting of 80% by weight of AMPS units neutralized with NH₃, and of 20% by weight of Genapol T-250 methacrylate units [units of formula (III) in which R₁=CH₃, R₄=C₁₆-C₁₈ and x=25];

[0128] a copolymer crosslinked with allyl methacrylate, consisting of 90% by weight of AMPS units neutralized with NH₃, and of 10% by weight of Genapol LA-070 methacrylate units [units of formula (III) in which R₁=H, R₄=C₁₂-C₁₄ and x=7].

EXAMPLES OF COMPOSITIONS

[0129] The examples which follow illustrate the invention without being limiting in nature. The amounts are indicated as percentages by weight, except where otherwise mentioned.

Example 1 Aqueous Gel for Skin Care (Moisturization and Radiance of the Complexion)

[0130] Crosslinked copolymer of AMPS (*)  2% Magnesium ascorbyl phosphate  2% Demineralized water qs 100%

[0131] The gel obtained has a viscosity of about 20 poises (2.0 Pa.s), the viscosity being measured at about 25° C. with a Rheomat 180 machine using a No. 3 spindle, at 200 s⁻¹. The gel has a very smooth appearance. The viscosity of the same gel without magnesium ascorbyl phosphate is about 26 poises, (2.6 Pa.s).

COMPARATIVE EXAMPLES

[0132] Example 1 was repeated, replacing the amphiphilic polymer used according to the invention, with polymers of the prior art: Hostacerin AMPS (AMPS homopolymer sold by the company Hoechst-Clariant) and Sepigel 305 (crosslinked anionic copolymer that is substantially water-soluble, consisting of units derived from the reaction between (i) acrylamide, (ii) 2-acrylamido-2-methylpropanesulphonic acid, and (iii) at least one compound containing olefinic polyunsaturation, sold by the company Seppic). The viscosity of the gel is measured with and without addition of 0.1% by weight of magnesium ascorbyl phosphate (MAP) (viscosity measured at about 25° C. with a Rheomat 180 machine using a No. 3 spindle, at 200 s⁻¹)

[0133] As shown in the table below, a large variation in viscosity is observed with these polymers of the prior art when an electrolyte is added thereto. Example of the Comparative Comparative invention Example 1 Example 1a with- with with out with out with out with Polymers MAP 1% MAP MAP 1% MAP MAP 1% MAP Amphi- philic polymer of 2% 2% the invention Hostacerin AMPS 2% 2% Sepigel 2% 2% 305 Viscosity 26.6 20.5 42.4 19.9 24.5 0.62 poises poises poises poises poises poises (2.66 Pa.s) (2.05 Pa.s) (4.24 Pa.s) (1.99 Pa.s) (2.45 Pa.s) (0.062 Pa.s) Variation −23% −53% −97% in viscosity

[0134] The variation in the viscosity by further addition of electrolyte is much smaller with the amphiphilic polymer used in the composition of the invention than with the gelling polymers of the prior art.

Example 2 Facial Care Cream (O/W Emulsion)

[0135] Oily phase: Mineral oil 5% Cyclohexadimethylsiloxane 5% Preserving agent qs %

[0136] Aqueous phase: Magnesium ascorbyl phosphate 1% Crosslinked copolymer of AMPS (*) 2% Preserving agent 0.2% Demineralized water qs 100%

[0137] Procedure: The constituents of the aqueous phase are mixed together with stirring until homogeneous, and the prehomogenized oily phase is introduced into this aqueous phase with stirring.

[0138] The cream obtained is a stable, homogeneous white cream that is soft on application and is capable of treating facial skin, and in particular of improving the radiance of the complexion.

Comparative Example 2

[0139] Example 2 was repeated, replacing the amphiphilic polymer used according to the invention with Sepigel 305. The emulsion obtained is very fluid and demixes immediately (separation of the aqueous phase and the oily phase with release of oil at the surface).

Example 3 Facial Care Cream (O/W Emulsion)

[0140] Oily phase: Mineral oil 5% Cyclohexadimethylsiloxane 5% Preserving agent qs %

[0141] Aqueous phase: Magnesium sulphate 0.5% Crosslinked copolymer of AMPS (*) 3% Preserving agent 0.2% Demineralized water qs 100%

[0142] Procedure: The copolymer is dispersed in water (it is made to swell) and the magnesium sulphate predissolved in a small amount of water is added to this gel. The mixture is stirred until homogeneous and the prehomogenized oily phase is introduced into this aqueous phase with stirring.

[0143] The cream obtained is a stable, homogeneous white cream that is soft on application and is capable of treating facial skin.

Example 4 Foundation

[0144] Phase A: Uncoated pigments 6% Phenyltrimethicone 8%

[0145] Phase B: Crosslinked copolymer of AMPS(*) 2%

[0146] Phase C: Magnesium ascorbyl phosphate 1% Preserving agents 0.5% Water qs 100%

[0147] This composition was prepared in the following manner: phase A is prepared in a first stage. Phase B is then dispersed in phase C (water). Phase A is then dispersed in (B+C).

[0148] The composition thus obtained is stable over time.

Example 5 Facial Care Cream Containing Dead Sea Salts

[0149] Oily phase: Mineral oil 5% Cyclohexadimethylsiloxane 5% Preserving agent qs %

[0150] Aqueous phase: Mixture of Dead Sea salts 0.3% Crosslinked copolymer of AMPS (*)   2% Preserving agent 0.2% Demineralized water qs 100% # with NH₃, and of 10% by weight of Genapol LA-070 methacrylate units [units of formula (III) in which # R₁ = H, R₄ = C₁₂-C₁₄ and x = 7].

[0151] The amount of Dead Sea salts is indicated as active material.

[0152] Procedure: The copolymer is dispersed in water (it is made to swell) and the mixture of Dead Sea salts is then added. The resulting mixture is stirred until homogeneous and the prehomogenized oily phase is introduced to this aqueous phase with stirring.

[0153] A fine emulsion which constitutes a thick, shiny cream is obtained. 

1. Composition for topical application, including an aqueous phase comprising at least one electrolyte and at least one amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion.
 2. Composition according to claim 1, characterized in that the hydrophobic portion of the amphiphilic polymer contains from 6 to 50 carbon atoms.
 3. Composition according to the preceding claim, characterized in that the hydrophobic portion of the amphiphilic polymer contains from 6 to 22 carbon atoms.
 4. Composition according to the preceding claim, characterized in that the hydrophobic portion of the amphiphilic polymer contains from 6 to 18 carbon atoms.
 5. Composition according to the preceding claim, characterized in that the hydrophobic portion of the amphiphilic polymer contains from 12 to 18 carbon atoms.
 6. Composition according to any one of the preceding claims, characterized in that the amphiphilic polymers are partially or totally neutralized with a mineral or organic base.
 7. Composition according to any one of the preceding claims, characterized in that the amphiphilic polymers have a number-average molecular weight ranging from 1000 to 20 000 000 g/mol.
 8. Composition according to the preceding claim, characterized in that the number-average molecular weight ranges from 20 000 to 5 000 000 g/mol.
 9. Composition according to the preceding claim, characterized in that the number-average molecular weight ranges from 100 000 to 1 500 000 g/mol.
 10. Composition according to any one of the preceding claims, characterized in that an aqueous solution containing 1% by weight of the said polymers has, at a temperature of 25° C., a viscosity, measured using a Brookfield viscometer with a No. 7 needle, ranging from 20 000 mpa.s to 100 000 mpa.s.
 11. Composition according to any one of the preceding claims, characterized in that the amphiphilic polymers are prepared by free-radical precipitation polymerization in tert-butanol.
 12. Composition according to any one of the preceding claims, characterized in that the amphiphilic polymers are crosslinked or non-crosslinked.
 13. Composition according to the preceding claim, characterized in that the amphiphilic polymers are crosslinked.
 14. Composition according to the preceding claim, characterized in that the crosslinking agent(s) is(are) chosen from compounds containing olefinic polyunsaturation.
 15. Composition according to the preceding claim, characterized in that the crosslinking agent(s) is(are) chosen from methylenebisacrylamide, allyl methacrylate and trimethylolpropane triacrylate (TMPTA).
 16. Composition according to any one of claims 13 to 15, characterized in that the degree of crosslinking preferably ranges from 0.01 mol % to 10 mol % and more particularly from 0.2 mol % to 2 mol % relative to the polymer.
 17. Composition according to any one of the preceding claims, characterized in that the ethylenically unsaturated monomer containing a sulphonic group is chosen from vinylsulphonic acid, styrenesulphonic acid, (meth)acrylamido(C₁-C₂₂)alkyl-sulphonic acids, N-(C₁-C₂₂)alkyl(meth)acrylamido-(C₁-C₂₂)alkylsulphonic acids, and also partially or totally neutralized forms thereof.
 18. Composition according to the preceding claim, characterized in that the ethylenically unsaturated monomer containing a sulphonic group is chosen from acrylamidomethanesulphonic acid, acrylamidoethanesulphonic acid, acrylamidopropane-sulphonic acid, 2-acrylamido-2-methylpropanesulphonic acid, methacrylamido-2-methylpropanesulphonic acid, 2-acrylamido-n-butanesulphonic acid, 2-acrylamido-2,4,4-trimethylpentanesulphonic acid, 2-methacrylamidododecylsulphonic acid or 2-acrylamido-2,6-dimethyl-3-heptanesulphonic acid, and also partially or totally neutralized forms thereof.
 19. Composition according to either of claims 17 and 18, characterized in that the ethylenically unsaturated monomer containing a sulphonic group is 2-acrylamido-2-methylpropane-sulphonic acid (AMPS), and also partially or totally neutralized forms thereof.
 20. Composition according to the preceding claim, characterized in that the amphiphilic polymers are chosen from random polymers of AMPS modified by reaction with an n-mono(C₆-C₂₂)alkylamine or a di-n-(C₆-C₂₂) alkylamine.
 21. Composition according to either of claims 19 and 20, characterized in that the amphiphilic polymers of AMPS also contain at least one ethylenically unsaturated monomer not comprising a fatty chain.
 22. Composition according to the preceding claim, characterized in that the ethylenically unsaturated monomer not comprising a fatty chain is chosen from (meth)acrylic acids and β-substituted alkyl derivatives thereof, and esters thereof obtained with monoalcohols or mono- or polyalkylene glycols, or alternatively from (meth)acrylamides, vinylpyrrolidone, maleic anhydride, itaconic acid or maleic acid, or mixtures of these compounds.
 23. Composition according to any one of the preceding claims, characterized in that the amphiphilic polymers are chosen from amphiphilic copolymers of AMPS and of at least one ethylenically unsaturated hydrophobic monomer comprising at least one hydrophobic portion containing from 6 to 50 carbon atoms.
 24. Composition according to the preceding claim, characterized in that the hydrophobic portion contains from 6 to 22 carbon atoms.
 25. Composition according to the preceding claim, characterized in that the hydrophobic portion contains from 6 to 18 carbon atoms.
 26. Composition according to the preceding claim, characterized in that the hydrophobic portion contains from 12 to 18 carbon atoms.
 27. Composition according to any one of claims 23 to 26, characterized in that the ethylenically unsaturated hydrophobic monomer is chosen from the acrylates or acrylamides of formula (I) below:

in which R₁ and R₃, which may be identical or different, denote a hydrogen atom or a linear or branched C₁-C₆ alkyl radical (preferably methyl); Y denotes O or NH; R₂ denotes a hydrophobic hydrocarbon-based radical containing at least from 6 to 50 carbon atoms, more preferably from 6 to 22 carbon atoms, even more preferably from 6 to 18 carbon atoms and more particularly from 12 to 18 carbon atoms; x denotes a number of moles of alkylene oxide and ranges from 0 to
 100. 28. Composition according to the preceding claim, characterized in that the hydrophobic radical R₂ is chosen from linear, branched or cyclic C₆-C₁₈ alkyl radicals; C₆-C₁₈ alkylperfluoro radicals; the cholesteryl radical or a cholesterol ester; aromatic polycyclic groups.
 29. Composition according to either of claims 27 and 28, characterized in that the monomer of formula (I) also comprises at least one alkylene oxide unit (x≧1).
 30. Composition according to any one of claims 27 to 29, characterized in that the monomer of formula (I) also comprises at least one polyoxyalkylenated chain.
 31. Composition according to the preceding claim, characterized in that the polyoxyalkylenated chain consists of ethylene oxide units and/or of propylene oxide units.
 32. Composition according to the preceding claim, characterized in that the polyoxyalkylenated chain consists solely of ethylene oxide units.
 33. Composition according to any one of claims 27 to 32, characterized in that the number of moles of alkylene oxide ranges from 3 to
 100. 34. Composition according to the preceding claim, characterized in that the number of moles of alkylene oxide ranges from 3 to
 50. 35. Composition according to the preceding claim, characterized in that the number of moles of alkylene oxide ranges from 7 to
 25. 36. Composition according to any one of claims 23 to 28, characterized in that the amphiphilic polymer of AMPS is chosen from: crosslinked or non-crosslinked, neutralized or non-neutralized copolymers comprising from 15% to 60% by weight of AMPS units and from 40% to 85% by weight of (C₈-C₁₆)alkyl (meth)acrylamide units or of (C₈-C₁₆)alkyl (meth)acrylate units relative to the polymer; terpolymers comprising from 10 mol % to 90 mol % of acrylamide units, from 0.1 mol % to 10 mol % of AMPS units and from 5 mol % to 80 mol % of n-(C₆-C₁₈)alkylacrylamide units relative to the polymer.
 37. Composition according to any one of claims 23 to 28, characterized in that the amphiphilic polymer of AMPS is chosen from: non-crosslinked copolymers of partially or totally neutralized AMPS and of n-dodecyl or n-hexadecyl methacrylate; crosslinked or non-crosslinked copolymers of partially or totally neutralized AMPS and of n-dodecylmethacrylamide.
 38. Composition according to claims 23 to 35, characterized in that the amphiphilic polymer of AMPS is chosen from copolymers consisting of 2-acrylamido-2-methylpropanesulphonic acid (AMPS) units of formula (II) below:

in which X⁺ is a proton, an alkali metal cation, an alkaline-earth metal cation or the ammonium ion, and of units of formula (III) below:

in which x denotes an integer ranging from 3 to 100, preferably from 5 to 80 and more preferably from 7 to 25; R₁ has the same meaning as that given above in formula (I) and R₄ denotes a linear or branched C₆-C₂₂ and more preferably C₁₀-C₂₂ alkyl.
 39. Composition according to the preceding claim, characterized in that x=25, R₁ is methyl and R₄ is n-dodecyl, n-hexadecyl or n-octadecyl.
 40. Composition according to claim 27 or 38, characterized in that the % molar proportion of units of formula (I) or of units of formula (III) in the polymers ranges from 50.1% to 99.9%.
 41. Composition according to claim 27 or 38, characterized in that the % molar proportion of units of formula (I) or of units of formula (III) in the polymers ranges from 0.1% to 50%.
 42. Composition according to any one of the preceding claims, characterized in that the amount of amphiphilic polymer(s) ranges from 0.01% to 30% by weight of active material, preferably from 0.1% to 10% by weight of active material and more preferably from 0.1% to 5% by weight of active material relative to the total weight of the composition.
 43. Composition according to any one of the preceding claims, characterized in that the electrolyte is a mono-, di- or trivalent metal salt.
 44. Composition according to the preceding claim, characterized in that the salt is chosen from barium, calcium, strontium, sodium, potassium, magnesium, beryllium, yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, lithium, tin, zinc, manganese, cobalt, nickel, iron, copper, rubidium, aluminium, silicon and selenium salts, and mixtures thereof.
 45. Composition according to any one of the preceding claims, characterized in that the electrolyte consists of ions chosen from carbonate, bicarbonate, sulphate, phosphate, sulphonate, glycerophosphate, borate, bromide, chloride, nitrate, acetate, hydroxide and persulphate ions, ions of α-hydroxy acids, ions of fruit acids, ions of β-hydroxy acids and ions of amino acids.
 46. Composition according to any one of the preceding claims, characterized in that the electrolyte is chosen from magnesium chloride, potassium chloride, sodium chloride, calcium chloride, magnesium bromide and the mixture of Dead Sea salts, and mixtures thereof.
 47. Composition according to any one of the preceding claims, characterized in that the electrolyte is introduced in the form of a thermal spring water and/or a mineral water.
 48. Composition according to any one of the preceding claims, characterized in that the electrolyte is chosen from salts derived from vitamins, and salts of acidic active agents.
 49. Composition according to any one of the preceding claims, characterized in that the amount of electrolyte(s) ranges from 0.01% to 20% and preferably from 0.01% to 10% by weight relative to the total weight of the composition.
 50. Composition according to any one of the preceding claims, characterized in that the physiologically acceptable medium consists of water or of water and at least one organic solvent chosen from the group consisting of lower alcohols containing from 1 to 8 carbon atoms, polyols, glycols, sorbitol and sugars, and mixtures thereof.
 51. Composition according to any one of the preceding claims, characterized in that it also comprises at least one oily phase.
 52. Composition according to any one of the preceding claims, characterized in that it is a care product and/or a hygiene product, a make-up product or an antisun product.
 53. Emulsion comprising an oily phase dispersed in an aqueous phase, characterized in that it is free of emulsifier and in that it contains at least one amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion.
 54. Emulsion according to the preceding claim, characterized in that it is in accordance with the composition according to any one of claims 1 to
 51. 55. Cosmetic use of a cosmetic composition according to any one of claims 1 to 51 or of a cosmetic emulsion according to claim 53 or 54, to treat, care for and/or make up the facial and/or body skin, mucous membranes (lips), the scalp and/or keratin fibres.
 56. Use of a composition according to any one of claims 1 to 51 or of an emulsion according to claim 53 or 54, for the manufacture of a composition intended to treat sensitive skin and/or a sensitive scalp.
 57. Cosmetic process for treating keratin materials, characterized in that a composition according to any one of claims 1 to 51 or an emulsion according to claim 53 or 54 is applied to the keratin materials.
 58. Use of an amphiphilic polymer including at least one ethylenically unsaturated monomer containing a sulphonic group, in free form or partially or totally neutralized form and comprising at least one hydrophobic portion, to obtain a stable cosmetic or dermatological composition containing at least one electrolyte. 